Managing the potential risk of engineered nanomaterials
MARINA (MAnaging RIsks of NAnoparticles) was a 39 month specific targeted European research project funded by the European Commission under FP6 from 2011-2015.
Led by Dr. Lang Tran, Institute of Occupational Medicine (IOM), the project involved a global consortium of 47 partners in total.
MARINA aimed to develop specific reference methods for all the main steps in managing the potential risk of engineered nanomaterials (ENM). It addressed the four central themes in the risk management paradigm for ENM: Materials, Exposure, Hazard and Risk.
The methods developed by MARINA are based on beyond-state-of-the-art understanding of the properties, interaction and fate of ENM in relation to human health and the quality of the environment and either (newly developed or adapted from existing ones but, ultimately, they were compared/validated and harmonised/standardised as reference methods for managing the risk of ENM.
MARINA developed a strategy for risk management including monitoring systems and measures for minimising massive exposure via explosion or environmental spillage.
A final report summary of the MARINA project is available to download here
In addition, the research undertaken as part of MARINA has led to publication of the following peer-reviewed papers co-authored by IOM/SAFENANO:
Bos PMJ, Gottardo S, Scott-Fordsmand JJ, van Tongeren M, et al. 2015, "The MARINA Risk Assessment Strategy: A Flexible Strategy for Efficient Information Collection and Risk Assessment of Nanomaterials," International Journal of Environmental Research and Public Health, 12(2), 15007-15021.
Ding Y, Stahlmecke B, Sanchez Jimenez A, Tuinman IL, et al. 2015, "Dustiness and Deagglomeration Testing: Interlaboratory Comparison of Systems for Nanoparticle Powders," Aerosol Science and Technology, 49(12), 1222-1231.
Farcal L, Andon FT, Di Cristo L, Rotoli BM, et al. 2015, "Comprehensive In Vitro Toxicity Testing of a Panel of Representative Oxide Nanomaterials: First Steps towards an Intelligent Testing Strategy," PLoS One, 10(5), e0127174.
Nowack B, Bornhoft N, Ding Y, Riediker M, et al. 2015, "The Flows of Engineered Nanomaterials from Production, Use, and Disposal to the Environment," in Indoor and Outdoor Nanoparticles, Mar Viana eds, Springer International Publishing.
Ding Y, and Riediker M. 2015, "A system to assess the stability of airborne nanoparticle agglomerates under aerodynamic shear," Journal of Aerosol Science, 88, 98-108.
Oomen AG, Bleeker EAJ, Bos PMJ, van Broekhuizen F, et al. 2015, "Grouping and Read-Across Approaches for Risk Assessment of Nanomaterials," International Journal of Environmental Research and Public Health, 12(10), 13415-13434.