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Hazard and risk assessment strategies for nanoparticle exposures: how far have we come in the past 10 years?

Date: 01/10/2018

A recent review by David B Warheit, titled ‘Hazard and risk assessment strategies for nanoparticle exposures: how far have we come in the past 10 years?’ has been published. The review provides an up-to-date summary on the progress of hazard and risk assessment of nanomaterials.

The review documents some of the conceptual planning efforts, implementation strategies/activities, and research accomplishments over the past 10 years. It also highlights the numerous challenges remaining in providing accurate health and environmental decisions on a variety of nanomaterial types.

The author highlights the following areas as necessary for improvement, including better information on:

  • Routes of exposure to nanomaterials (pulmonary, oral and dermal);
  • Standardised nanomaterial characterisation issues, including a nanomaterial definition that can be scientifically justified;
  • Improvements in research methodologies, protocols and implementation of studies, such as time-course and dose-response issues; and
  • Development of robust in vitro methodologies that can be validated for representation in vivo effects in standardised guideline toxicology testing.

The full review can be accessed here.

Source: NCBI

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