GRACIOUS is a 3 year Horizon 2020 (H2020) project, led by Heriot-Watt University, which commenced on the 1st January 2018.
The GRACIOUS project aims to develop a framework that supports the risk assessment of nanomaterials. The framework will facilitate grouping and read-across of nanomaterials based on physiochemical, release, exposure, environmental fate, toxiokinetic and toxicological information thus reducing the need to assess nanomaterials on a case by case basis.
Industry has the ability to modify the chemical and physical characteristics of materials at the nanoscale leading to a wide array of nanomaterials (NMs) varying in size, morphology and surface characteristics. Due to financial, time and ethical considerations, safety testing of every unique nanomaterial for their potential adverse effects is virtually impossible. For these reasons, more efficient ways to obtain safety information are needed.
Bringing together 23 partners spanning Europe and the USA, GRACIOUS aims to generate a highly innovative science-based framework accounting for those issues with the ultimate aim of streamlining the risk assessment process. The framework will be delivered as a practical e-tool, fit-for-purpose for various key (regulatory and industrial) stakeholders, who are engaged from the start of the project. IOM are involved in a number of aspects of the project including the establishment of grouping hypotheses, the development of in silico approaches, and in data curation.