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Toxicology

Toxicology reading list 

The following reading list details what we consider to be some of the most informative papers and reports available relating to the toxicology of nanomaterials.

This list is reviewed and updated regularly to capture the most recent scientific literature.

Key papers

The carcinogenic effect of various multi-walled carbon nanotubes (MWCNTs) after intraperitoneal injection in rats.
  Rittinghausen S, Hackbarth S, Creutzenberg O, et al. (2014). Particle and Fibre Toxicology; 11:59.
Understanding nanoparticle cellular entry: A physicochemical perspective.
  Beddoes CM, Case CP, Briscoe WH. (2015). Advances in Colloid and Interface Science; 218C: 48-68.

Interlaboratory evaluation of rodent pulmonary responses to engineered nanomaterials: the NIEHS Nano GO Consortium.
   Bonner JC, Silva RM, Taylor AJ, Brown JM, et al. (2013). Environmental Health Perspectives; 121(6): 676-682.
   View abstract.  

Physicochemical characteristics of nanomaterials that affect pulmonary inflammation.
   Braakhuis HM, Park MV, Gosens I, et al. (2014). Particle & Fibre Toxicology; 11:18.
   View abstract.  

The biologically effective dose in inhalation nanotoxicology.
   Donaldson K, Schinwald A, Murphy F, Cho WS, et al. (2012). Accounts of Chemical Research.
   View abstract.  

Nanoparticles and the cardiovascular system: a critical review.
   Donaldson K, Duffin R, Langrish JP, Miller MR, et al. (2013). Nanomedicine; 8(3): 403-423.
   View abstract.

Comparative inhalation toxicity of multi-wall carbon nanotubes, graphene, graphite nanoplatelets and low surface carbon black.
   Ma-Hock L, Strauss V, Treumann S, Kuttler K, et al. (2013). Particle and Fibre Toxicology; 10(1): 23.
   View abstract.

Distribution and persistence of pleural penetrations by multi-walled carbon nanotubes.
   Mercer RR, Hubbs AF, Scabilloni JF, Wang L, et al. (2010). Particle and Fibre Toxicology; 7: 28.
   View abstract. 

Distribution and fibrotic response following inhalation exposure to multi-walled carbon nanotubes.
   Mercer RR, Scabilloni JF, Hubbs AF, Battelli LA, et al. (2013). Particle and Fibre Toxicology; 10(1): 33.
   View abstract. 

Quantification of quantum dot murine skin penetration with UVR barrier impairment.
   Mortensen LJ, Jatana S, Gelein R, De Benedetto A, et al. (2013). Nanotoxicology; 7: 1386-1398.
   View abstract.

Biological interactions of graphene-family nanomaterials: an interdisciplinary review.
   Sanchez VC, Jachak A, Hurt RH, Kane AB. (2012). Chemical Research in Toxicology; 25(1): 15-34.
   View abstract. 

Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes.
   Sargent L, Porter D, Staska L, Hubbs A, et al. (2014). Particle and Fibre Toxicology; 11(1): 3.
   View abstract. 

The threshold length for fiber-induced acute pleural inflammation: shedding light on the early events in asbestos-induced mesothelioma. 
   Schinwald A, Murphy F, Prina-Mello A, Poland C, et al. (2012). Toxicological Sciences; 128: 461-470.
   View abstract.  

Use of metal oxide nanoparticle band gap to develop a predictive paradigm for oxidative stress and acute pulmonary inflammation.
   Zhang H, Ji Z, Xia T, Meng H, et al. (2012). ACS Nano; 6(5): 4349-4368.
   View abstract.


Key reports

Current Intelligence Bulletin 63: Occupational exposure to titanium dioxide.
   NIOSH. (2011). Atlanta: National Institute for Occupational Safety and Health.
   View report.

Current Intelligence Bulletin 65: Occupational exposure to carbon nanotubes and nanofibers.
   NIOSH. (2013). Atlanta: National Institute for Occupational Safety and Health.
   View report.  

Dermal absorption of nanomaterials.
   Poland CA, Read SAK, Varet J, Carse G, et al. (2013). Copenhagen: Danish Ministry of the Environment.
   View report.

Key books

The toxicology of carbon nanotubes. 
   Donaldson K, Poland C, Duffin R, Bonner J, eds. (2012). Cambridge University Press. 
   View book. 

Nanomaterials - toxicity, health and environmental Issues.
   Kumar C, ed. Wiley-VCH. 333 pp.
   View book.

Nanotoxicology: progress toward nanomedicine, Second Edition.
   Nancy A, Monteiro-Riviere C, Tran L, eds. (2014). CRC Press. 
   View book.  

Particle toxicology.
   Donaldson K, Borm P, eds. (2007). CRC Press. 
   View book. 

Adverse effects of engineered nanomaterials: exposure, toxicology, and impact on human health.
   Fadeel B, Pietroiusti A, Shvedova A, eds. (2012). Elsevier Academic Press. 
   View book.