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Physico-chemical Characterisation

Physico-chemical characterisation reading list

The following reading list details what we consider to be some of the most informative papers and reports available relating to the physico-chemical characterisation of nanomaterials.  

This list is reviewed and updated regularly to capture the most recent scientific literature.

Key papers

Nanomaterial characterization: considerations and needs for hazard assessment and safety evaluation. 
   Boverhof DR, David RM. (2010). Analytical & Bioanalytical Chemistry; 396(3): 953-961.
   View abstract.


Nanoparticle characterization: state of the art, challenges, and emerging technologies.
   Cho EJ, Holback H, Liu KC, Abouelmaqd SA, et al. (2013). Molecular Pharmacology; 10(6): 2093-2110.
   View abstract.


Experimental techniques for the characterization of carbon nanoparticles – a brief overview.
   Kempiński W, Loś S, Kempiński M, et al. (2014). Bellstein Journal of Nanotechnology; 13(5): 1760-6.
   View abstract.


Techniques for physicochemical characterization of nanomaterials.
   Lin P-C, Lin S, Wang PC, Sridhar R. (2013). Biotechnology Advances, 32(4): 711-26.
   View abstract.

A strategy for grouping of nanomaterials based on key physico-chemical descriptors as a basis for safer-by-design NMs.
   Lynch I, Weiss C, Valsami-Jones E. (2014). Nanotoday. 9(3): 266-270.
   View abstract.


Analytical methods to assess nanoparticle toxicity.
   Marquis BJ, Love SA, Braun KL, Haynes CL. (2009). The Analyst; 134(3): 425-439. 
   View abstract.


(Q)SAR modelling of nanomaterial toxicity: A critical review.
   Oksel C, Ma CY, Liu JJ, et al. (2015). Particuology. [in press]
   View abstract.
 
Characterization of nanomaterials for toxicological studies.
   Powers KW, Carpinone PL, Siebein KN. (2012). Methods in Molecular Biology; 926: 13-32.
   View abstract.


How meaningful are the results of nanotoxicity studies in the absence of adequate material characterization?
   Warheit DB. (2008). Toxicological Sciences; 101(2): 183-185.
   View abstract.


Practical considerations for conducting ecotoxicity test methods with manufactured nanomaterials: what have we learnt so far?
   Handy RD, van den Brink N, Chappell M, Mühling M, et al. (2012). Ecotoxicology; 21: 933-972.
   View abstract.


Key reports

Metrology for nanoparticle characterisation: instruments, standard methods and reference materials.
   Co-Nanomet. (2010). European Workshop, 28-29 April 2010, CCN Congress Centre, Nuremberg, Germany.
   View report.


Guidance on sample preparation and dosimetry for the safety testing of manufactured nanomaterials.
   OECD. (2012). Series on the Safety of Manufactured Nanomaterials, No. 36, ENV/JM,MONO(2012)40.
   View report.


Report of the OECD Expert Meeting on the Physical Chemical Properties of Manufactured Nanomaterials and Test Guidelines.
   OECD. (2014). Series on the Safety of Manufactured Nanomaterials, No. 41, ENV/JM,MONO(2014)15.
   View report.